Medicover Hospitals, Hitech City has successfully performed a high-risk Living Donor Liver Transplant (LDLT) to a 43-year-old suffering from advanced decompensate chronic liver disease, marking a significant achievement in managing one of the most critical liver failure cases. The transplant was performed on 18 October 2025, when the patient was in an extremely critical condition. Liver function tests showed severe deterioration, with bilirubin levels reaching 37 mg/dL, indicating end-stage liver failure and the urgent need for transplantation.

Speaking about the case, Dr. Kishore Reddy, Lead Liver Transplant Surgeon described the case as a highly challenging one due to the patient’s critical neurological status and severely compromised liver function. He mentioned that precise surgical execution and coordinated multidisciplinary care were crucial in achieving a successful outcome. 

The patient’s care was led by a multidisciplinary liver transplant team. Dr. Krishnagopal Bhandari and Dr. Ajay Shesherao Shinde, Consultant Gastroenterologists & Liver Transplant Physicians, played a key role in pre-transplant optimization and post-transplant medical management. Dr. SBS Srinivas, Head of Liver Transplant Anesthesia and Liver Critical Care, led the preoperative anesthesia and intensive care management, ensuring stability during and after the complex procedure.

Due to prolonged critical illness, the patient developed critical illness–related polyneuromyopathy, resulting in severe muscle weakness. With structured physiotherapy and rehabilitation, he showed gradual improvement. Liver parameters normalized steadily, immunosuppressive therapy was optimized, and all surgical drains were removed. At discharge, the patient was clinically stable, tolerating oral diet, and continuing rehabilitation.