President Donald Trump's administration is cutting another $450 million in grants to Harvard University a day after the Ivy League school pushed back against government allegations that it's a hotbed of liberalism and antisemitism.

In a letter to Harvard on Tuesday, a federal antisemitism task force said Harvard will lose grants from eight federal agencies in addition to $2.2 billion that was previously frozen by the Trump administration.

The letter said Harvard has become a "breeding ground for virtue signalling and discrimination" and faces a "steep, uphill battle" to reclaim its legacy as a place of academic excellence.

"There is a dark problem on Harvard's campus, and by prioritizing appeasement over accountability, institutional leaders have forfeited the school's claim to taxpayer support," the letter said.

It was signed by officials at the Education Department, Health and Human Services and the General Services Administration.

Hours after the latest cuts Tuesday, Harvard filed a legal challenge to several sanctions imposed by the Trump administration in recent weeks. It was filed as an update to the university's April lawsuit seeking to block the initial $2.2 billion freeze.

Harvard has faced escalating sanctions from the White House after becoming the first U.S. university to openly defy the government's demands to limit pro-Palestinian activism and end diversity, equity and inclusion practices.